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Individual Component PSD in Co-Micronized API Blends

Utilize SPES Technology for Particle Size Characterization

Active Pharmaceutical Ingredients (APIs) often require particle size control and solubility enhancement with excipients to increase dissolution rates and solubility for APIs to be bioavailable. SPES (Single Particle Extinction and Scattering) technology can analyze individual components in API blends, extracting particle size distributions (PSDs), refractive indices (RIs), and numerical concentrations of individual components in blends.

• APIs frequently need particle size control and excipients to improve bioavailability

• Co-micronization is an effective way to micronize and blend APIs and excipients

• The SPES technology can characterize the size and optical properties of individual components in blends