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Prevent dehydration and phase changes in API hydrates using humidified air-swept classification.

 

API hydrates face significant risks during micronization, as mechanical heat and dry gases can cause dehydration and unwanted phase conversions. This whitepaper details a proven strategy using solid-state characterization to identify these risks early and employs humidified air-swept classification to rehydrate materials, ensuring the correct crystalline form is maintained at commercial scale.
  • Identify Phase Risks: Use solid-state characterization techniques like XRPD and DVS to detect potential dehydration and phase changes before they impact production.
  • Effective Rehydration: Discover how turbo-screen classifiers in humidified air provide superior rehydration compared to static storage methods.
  • Commercial Scalability: Review validation data from over 70 campaigns proving the robustness of this process for metric-ton scales.